Keywords |
Active biosensing, Artificial retina implants, Neurodegenerative pathologies treatment, Blindness treatment , Biocompatibility study, Biofuctionality, Bio-interface construction, CMOS structures, CVD diamond growth, Diamond electrodes, Electrical stimulation of neurons , Electrochemical sensing, In-vitro neural simulation and signal transfer, In-vivo sensing, ISFET device, Nanotechnology, Nanotransducer, Neural -interfacing concepts , Nanocrystalline diamond, Surface functionalisation, Surface patterning. |
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Project objectives: |
Development of biocompatible artificial CVD diamond nano-transducers for interfacing to neural cells for retina neuron stimulation. |
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Specific challenges: |
Demonstration of active, in-vivo, low threshold signal transfers between diamond FETs and retina cell’s neurons aiming at bio-electronic interfacing of complex matrix systems. |
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Expected impact: |
Gaining of important knowledge on construction and properties of nanocrystalline CVD diamond devices for bioelectronics and bio-sensing. High sensitivity, stability and device biocompatibility opens avenues for in-vivo electrical stimulation of neurons as a therapeutic approach for treatments of neurodegenerative pathologies as blindness and other disabilities. In exploring novel pathways that could ultimately result in the integration of bioelectronics and nanotechnology for “cell-diamond bioelectronics”. |
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